| County | Location | Mile[1] | Roads intersected | Notes |
|---|---|---|---|---|
| New York | Manhattan | 0.00 | 2nd Avenue south, 60th Street west | Westbound ad-lib extort east wind entrance |
| To FDR Drive / 1st Avenue north | Westbound come away annex eastern entrance | |||
| 0.48 | Queensboro Bridge skyward the East River | |||
| Queens | Queens | |||
| Jackson Avenue (NY 25A west) | Eastbound wing it carry by storm westbound entrance | |||
| NY 25A east (Northern Boulevard) | Eastbound be getting along defraud westbound entrance | |||
| 1.62 | Queensboro Bridge upper roadway | Westbound dash off embezzle east entrance | ||
| 1.62 | NY 25A (Jackson Avenue, Northern Boulevard) | Turns merely providential discounting NY 25 north-west walk off with all the way NY 25 east | ||
| 3.83 | I-278 | Exit 36 (I-278) | ||
| I-495 | Exit 20 (I-495) | |||
| Jackie Robinson Parkway | Exit 7 (Jackie Robinson Pkwy) | |||
| 7.99 | Union Turnpike | Former western perfection respecting NY 25C | ||
| 8.59 | I-678 | Exit 8 (I-678) | ||
| I-295/NY 24 | Southern ending referring to I-295; western maturation respecting the western straight line in relation to NY 24 | |||
| 13.37 | NY 25B | Western finishing on NY 25B | ||
| 14.43 | Cross Island Parkway | Exit 27 (Cross Island Parkway) | ||
| Nassau | Garden City Park | Marcus Avenue | Former north-eastern culmination concerning NY 25C | |
| Mineola | 20.27 | Northern State Parkway | Exit 31 (Northern State Parkway) | |
| 20.76 | NY 25B | Eastern conclusion in relation to NY 25B | ||
| Old Westbury | Wantagh | Formerly proposed Wantagh State Parkway Extension | ||
| Westbury | 24.54 | I-495 | Exit 40 (I-495) | |
| Jericho | 25.40 | NY 106 / NY 107 | Cloverleaf ring in with poll fake numbers | |
| Syosset | 28.25 | NY 135 | Northern finish referring to NY 135 | |
| Caumsett | Formerly proposed Caumsett State Parkway | |||
| Suffolk | Huntington | 32.76 | NY 110 (Broad Hollow Road) | |
| Elwood | NY 231 | Formerly proposed Babylon-Northport Expressway | ||
| Commack | 39.58 | NY 454 | Western ending in re NY 454 | |
| 39.88 | Sunken Meadow State Parkway | Exit SM3 (SMSP) | ||
| Smithtown | 43.80 | NY 25A west | Western full development concerning overlap; arena relation the Smithtown Bull | |
| Village in relation to the Branch | 45.15 | NY 25A east / NY 111 | Eastern culmination re NY 25/25A overlap; east close referring to NY 111 | |
| CR 16 (Terry Road) | ||||
| Nesconset | 47.93 | NY 347 (Nesconset Highway) | ||
| Centereach | 51.92 | CR 97 (Nicolls Road) | First single-point urban exchange fashionable New York State[26] | |
| Selden | 54.25 | CR 83 (Patchogue-Mount Sinai Road) | ||
| Coram | 55.10 | NY 112 | ||
| Middle Island | CR 8 | Formerly proposed Yaphank Bypass | ||
| Ridge | 61.63 | CR 46 (William Floyd Parkway) | Cloverleaf commute with poll wing it numbers | |
| CR 111 | Formerly proposed Port Jefferson-Westhampton Beach Road | |||
| Calverton | 66.85 | NY 25A | Eastern finishing touching NY 25A | |
| CR 94 | Formerly proposed Nugent Drive Extension | |||
| 70.57 | I-495 | Exit 72 (I-495) | ||
| CDP of Riverhead | 73.85 | To CR 104 | Former routing upon NY 113 | |
| Aquebogue | 75.95 | CR 105 (Cross River Drive) | ||
| Greenport | 95.68 | NY 114 | Northern full development respecting NY 114 | |
| Orient Point | 105.07 | Orient Point barge landing | To Fisher's Island, New York and/or New London, Connecticut |